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Thursday, December 1, 2022

New Findings on Rare Mucinous Ovarian Cancer May Change Tx

A global study of the microscopic patterns of cell growth in samples taken from women with this rare form of ovarian cancer may lead to treatment changes for some. Medscape Medical News

Preventing Doxorubicin-Induced Hand-Foot Syndrome

Dexamethasone plus wrist and ankle cooling may prevent hand-foot syndrome from doxorubicin in patients with ovarian cancer. The study was published as a preprint and has not yet been peer reviewed. First Look

Drug Companies Withdraw PARPi Indications for Ovarian Cancer

Zejula, Lynparza, and Rubraca have been voluntarily withdrawn for late-line ovarian cancer treatment indications over concerns surrounding an increased risk for death. Medscape Medical News

When Too Much Treatment Creates More Harm Than Good

Despite guidelines advising against intensive end-of-life care, many women with terminal ovarian cancer receive an aggressive intervention. Medscape Medical News

Large Benefit From Ovarian Function Suppression in Breast Cancer

Eight-year follow-up of the ASTRRA trial confirms and extends support for adding 2 years of ovarian function suppression with goserelin to tamoxifen, compared with tamoxifen alone. Medscape Medical News

Novel CAR T Therapy for Solid Tumors: 'Exciting Advance'

The approach, which combines a chimeric antigen receptor with an RNA vaccine, showed early efficacy against advanced testicular and ovarian cancers. Medscape Medical News

Immune System-Generated Antibodies Combat Ovarian Tumors in a Lab Study

The immune systems of ovarian cancer patients can produce antibodies against tumors, a cell-based study shows, and researchers suggest the finding could lead to a new type of immunotherapy. Reuters Health Information

Rucaparib Bests Chemo in Relapsed Ovarian Cancer

Results of the ARIEL4 study support the use of the PARP inhibitor rucaparib as an alternative to chemotherapy for patients with relapsed, BRCA1- or BRCA2-mutated ovarian cancer. Reuters Health Information

Complex Surgery 10 Times More Likely With Some Ovarian Tumors

Complex surgery is much more likely for advanced ovarian cancer in women with mesenchymal tumors and complex preoperative CT findings. Medscape Medical News

Virtual Exams for Routine Surveillance After Ovarian Cancer

Virtual visits may be a suitable alternative to the frequent in-person visits currently mandated for patients who are in remission from ovarian cancer. Medscape Medical News

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