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Wednesday, June 29, 2022

Large Benefit From Ovarian Function Suppression in Breast Cancer

Eight-year follow-up of the ASTRRA trial confirms and extends support for adding 2 years of ovarian function suppression with goserelin to tamoxifen, compared with tamoxifen alone. Medscape Medical News

Novel CAR T Therapy for Solid Tumors: 'Exciting Advance'

The approach, which combines a chimeric antigen receptor with an RNA vaccine, showed early efficacy against advanced testicular and ovarian cancers. Medscape Medical News

Immune System-Generated Antibodies Combat Ovarian Tumors in a Lab Study

The immune systems of ovarian cancer patients can produce antibodies against tumors, a cell-based study shows, and researchers suggest the finding could lead to a new type of immunotherapy. Reuters Health Information

Rucaparib Bests Chemo in Relapsed Ovarian Cancer

Results of the ARIEL4 study support the use of the PARP inhibitor rucaparib as an alternative to chemotherapy for patients with relapsed, BRCA1- or BRCA2-mutated ovarian cancer. Reuters Health Information

Complex Surgery 10 Times More Likely With Some Ovarian Tumors

Complex surgery is much more likely for advanced ovarian cancer in women with mesenchymal tumors and complex preoperative CT findings. Medscape Medical News

Virtual Exams for Routine Surveillance After Ovarian Cancer

Virtual visits may be a suitable alternative to the frequent in-person visits currently mandated for patients who are in remission from ovarian cancer. Medscape Medical News

Changing Landscape of Uterine and Ovarian Cancer in the US

The landscape of gynecologic cancer in the United States is changing rapidly and the risk of dying from uterine cancer is now similar to that for ovarian cancer among women overall, and roughly 60% higher among Black women, researchers say. Reuters Health Information

Trametinib: New Go-To for Low-Grade Serous Ovarian Carcinoma?

For the first time, a randomized trial has reported positive results in patients with this particular type of ovarian cancer. Medscape Medical News

Cancer Deaths Continue to Fall in EU, UK, Led by Ovarian Cancer

Mortality rates from most major cancers are predicted to continue falling in Europe and the UK in 2022, with a particularly striking reduction in deaths from ovarian cancer. Medscape Medical News

BRCA Testing Underused in Women With Ovarian Cancer

More than a decade after calls for universal screening for germline BRCA mutations in women with ovarian cancer, it remains underused. Medscape Medical News

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