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Thursday, December 1, 2022

Racial Disparities in Lung Cancer Start With Research

Improving lung cancer outcomes in Black communities will take more than lowering the screening age, experts say. Kaiser Health News

FDA Rejects Piziotinib for Certain Types of NSCLC

The drug was not approved for the treatment of patients with previously treated locally advanced or metastatic nonsmall cell lung cancer harboring HER2 exon 20 insertion mutations. Medscape Medical News

Over Half of Targetable NSCLC Patients Miss Out on Correct Tx

Most patients with advanced non–small cell lung cancer (NSCLC) have tumors with actionable mutations, but two thirds of them are not receiving targeted therapy owing to gaps in clinical practice. Medscape Medical News

Neoadjuvant Therapy Improves Survival in Metastatic Colon Cancer

Among patients with metastatic colon cancer with liver or lung lesions who received neoadjuvant therapy, survival was longer in comparison with patients who received adjuvant therapy, but only in nonacademic settings. Medscape Medical News

Annual Lung Cancer Screening Rates Still Low: Lots of Reasons Why

Fewer than 6% of high-risk smokers undergo annual lung cancer screening, as is recommended, even though the test can detect early lung cancer when it is still curable. Medscape Medical News

FDA Approves New Immunotherapy Combo for mNSCLC

The agency has approved the combination of tremelimumab (Imjudo) and durvalumab (Imfinzi) for use together with chemotherapy for patients with metastatic non–small cell lung cancer (mNSCLC). FDA Approvals

New FDA Approval Expands Use of Cemiplimab in NSCLC

The new approval expands use of the PD-1 inhibitor cemiplimab (Libtayo) to patients with advanced non–small cell lung cancer (NSCLC) irrespective of PD-LI expression. Medscape Medical News

Cancer Death Rate in US Declining by 2% Every Year: Report

The latest Annual Report to the Nation on the Status of Cancer notes that deaths from the disease have been falling by 2% from 2014 to 2019; the biggest decreases were in lung cancer and melanoma. Medscape Medical News

Gene Mutations May Drive Lung Cancer in Never-Smokers

A new retrospective analysis suggests small cell lung cancer (SCLC) has a different genomic profile among smokers than nonsmokers. MDedge News

Evidence Found Linking Air Pollution With Lung Cancer

Researchers have uncovered a potential mechanism whereby the air we breathe may trigger driver mutations already present in normal lung cells to cause cancer. MDedge News

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