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Genitourinary Cancer

Chemo for Early-Stage Prostate Cancer? RTOG 0521 Says Maybe

Chemotherapy for prostate cancer is currently limited to metastatic disease, but results from the Radiation Therapy Oncology Group (RTOG) 0521 trial indicate its possible usefulness in some cases of aggressive, early-stage disease. "The trial suggests that docetaxel chemotherapy may be an option to be discussed with selected men with high-risk prostate cancer," conclude the investigators,...

Paradigm Shift in Treatment of Testicular Seminoma?

SAN FRANCISCO — Retroperitoneal lymph node dissection (RPLND) could potentially be a first-line option for men with stage II A/B testicular seminoma in order to reduce long-term toxicity and secondary malignancies, suggest data from two new studies. Although RPLND is currently rarely used as first-line therapy in testicular seminoma, overall survival rates appear to be excellent,...

Recommendation or Suggestion?: Discussing Treatment Options Requires Precision

Originally published in "Discussions with Don S. Dizon" on The Oncologist.  One of the most valuable jobs I held following fellowship was working as a full-time deputy editor at UpToDate. My “territory” was breast, gynecologic, and genitourinary oncology, and I helped launch cancer survivorship and palliative care. I learned to really and critically read the literature,...

New treatment options for metastatic renal cell carcinoma

During the last decade, the treatment of advanced or metastatic renal cell carcinoma (RCC) was revolutionised with the advent of antiangiogenic drugs and tyrosine-kinase inhibitors (TKI). Consequently, cytokines treatment such as interferon-α and interleukin-2 (IL-2), which were the standard-of-care treatment until then, were quickly abandoned or restricted to very selected situations (like IL-2). Several...

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016

ESMO/ASCO Global Curriculum Working Group Chair Christian Dittrich, MD, Professor of Medicine Head of 3rd Medical Department—Centre for Oncology and Haematology, Kaiser Franz Josef-Spital, Vienna, Austria Members Emilio Alba Conejo, MD Director of UGCI Oncology Intercentros, Hospital Universitario Virgen de la Victoria y Regional de Malaga, Malaga, Spain Rossana Berardi, MD, Professor of Medical Oncology Head of Department of Medical Oncology, Università...

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