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Wednesday, August 17, 2022

New Blood Test Could Reshape Early CRC Screening

A new assay that identifies a specific combination of microRNA strands may expand colorectal cancer screening to younger ages in the face of rising rates of early-onset disease. Medscape Medical News

US Hot, Cold Spots of Young-Onset CRC May Help Target Interventions

Mortality from young-onset colorectal cancer varies across the United States, with hot spots of higher rates and cold spots of lower rates, which may help guide future interventions, say researchers. Medscape Medical News

Pregnancy, Breastfeeding, and More Linked to Lower CRC Risk

A new study shows that oral contraceptives, hormone replacement therapy, and pregnancy, among other factors, are associated with a decreased risk of developing colorectal cancer. Medscape Medical News

Sequential Salvage Therapies Prolong Metastatic CRC Survival

Patients with colorectal cancer (CRC) that progresses after one salvage regimen can benefit from another. The study was published as a preprint and has not yet been peer reviewed. First Look

New Insight on How a Western Diet May Cause Colorectal Cancer

A new study finds a strong link between a Western-style diet and colorectal cancer containing an abundant type of potentially carcinogenic Escherichia coli. Medscape Medical News

People Under 50 With Obesity May Need More CRC Prevention

Metabolic syndrome is positively linked with colorectal cancer before age 50 at similar rates to that of people who receive a diagnosis after age 50. Medscape Medical News

'Underwhelming' Improvements in mCRC Overall Survival

Overall survival for patients with metastatic colorectal cancer has improved over recent decades with the introduction of novel systemic therapies, but the gains have been modest at best, say experts. Medscape Medical News

Iatrogenic Tumor Seeding via Colonoscopy Unlikely

Biopsy of noncancerous sites after biopsy of a colorectal cancer confers no meaningfully higher risk of metachronous cancer, despite biologic plausibility. Medscape Medical News

Updated Guideline Prompts Younger People to Undergo CRC Screening

A new study shows that Americans are getting their first colonoscopies at 45 years old following the update to the US colorectal cancer screening guidelines. Medscape Medical News

Panitumumab Beats Bevacizumab in Left-Sided mCRC

The first trial comparing panitumumab or bevacizumab plus standard chemotherapy has shown that the former significantly improves survival in left-sided Ras wild type metastatic colorectal cancer. Medscape Medical News

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