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Thursday, December 1, 2022

Atezolizumab Bladder Cancer Indication Withdrawn in US

The manufacturer has voluntarily withdrawn the US indication that covered its use in certain patients with bladder and urinary tract cancers. Medscape Medical News

Intra-Arterial Chemo Improves Outcomes in Bladder Cancer

Adding intra-arterial chemo to standard BCG therapy may reduce recurrence risk for patients with non–muscle-invasive bladder cancer. The study was published as a preprint and has not yet been peer reviewed. First Look

Firefighting a Carcinogenic Occupation, Warn Experts

Firefighters have occupational exposure that meets five of the 10 criteria for being carcinogenic and is directly related to increased rates of mesothelioma and bladder cancer, say international experts. Medscape Medical News

BCG Vaccine Benefit in Non–Muscle Invasive Bladder Cancer?

Among patients with very high-risk but not high-risk disease, bacillus Calmette-Guérin more effectively delayed time to progression compared with transurethral resection of the bladder. Medscape Medical News

Simple Urine Test Could Improve Detection of Bladder Cancer

A test that detects a biomarker in urine samples has shown excellent performance for the detection of bladder cancer in two independent studies. Medscape Medical News

Overuse of Surveillance in Bladder Cancer, Despite Guidelines

Guidelines that recommend de-escalating surveillance in patients with low risk non–muscle-invasive bladder cancer are being ignored by clinicians. Medscape Medical News

Bladder Cancer Need Not Always Require Radical Cystectomy

Researchers involved in a large cohort study from three major institutions are calling for broader use of trimodal therapy for muscle-invasive bladder cancer. Medscape Medical News

COVID Has Led to Big Declines in Cancer Screenings, New Diagnoses

The large study helps quantify the extent to which the pandemic has affected new diagnoses of prostate, lung, bladder, and colorectal cancers in 2020. Medscape Medical News

How to Avoid Cystectomy in Muscle-Invasive Bladder Cancer

Nearly half the patients with muscle-invasive bladder cancer had clinical complete responses, showing that bladder-intact recurrence-free survival is possible. Medscape Medical News

To Stay: Two More Cancer Indications With ‘Dangling Approvals’

On the second day of a historic meeting, FDA advisers voted to keep the accelerated approvals for two immunotherapies for use in bladder cancer. Medscape Medical News

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