Urine Test Predicts Future Bladder Cancer 12 Years Before Symptoms
A 10-gene assay predicted future cases of urothelial cancer, the most common form of bladder cancer, with a high degree of sensitivity and specificity. Medscape Medical News
Gemcitabine-Docetaxel Effective Alternative to BCG in NMIBC
The chemotherapy duo performed better than expected as a stand-in for bacillus Calmette-Guérin (BCG), which is the gold standard for non–muscle-invasive bladder cancer but is currently in short supply. Medscape Medical News
Pembrolizumab Activity in BCG-Refractory Papillary Bladder Cancer
Pembrolizumab monotherapy showed promising antitumor activity for patients with high-risk non–muscle invasive bladder cancer that did not respond to standard treatment with BCG. Medscape Medical News
Judge Weighs Key Evidence Ahead of First Zantac Cancer Trial
Lawyers for a man who alleges he developed bladder cancer after taking heartburn drug Zantac urged a California judge on Thursday to allow expert testimony at an upcoming trial. Reuters Health Information
Atezolizumab Bladder Cancer Indication Withdrawn in US
The manufacturer has voluntarily withdrawn the US indication that covered its use in certain patients with bladder and urinary tract cancers. Medscape Medical News
Intra-Arterial Chemo Improves Outcomes in Bladder Cancer
Adding intra-arterial chemo to standard BCG therapy may reduce recurrence risk for patients with non–muscle-invasive bladder cancer. The study was published as a preprint and has not yet been peer reviewed. First Look
Firefighting a Carcinogenic Occupation, Warn Experts
Firefighters have occupational exposure that meets five of the 10 criteria for being carcinogenic and is directly related to increased rates of mesothelioma and bladder cancer, say international experts. Medscape Medical News
BCG Vaccine Benefit in Non–Muscle Invasive Bladder Cancer?
Among patients with very high-risk but not high-risk disease, bacillus Calmette-Guérin more effectively delayed time to progression compared with transurethral resection of the bladder. Medscape Medical News
Simple Urine Test Could Improve Detection of Bladder Cancer
A test that detects a biomarker in urine samples has shown excellent performance for the detection of bladder cancer in two independent studies. Medscape Medical News
Overuse of Surveillance in Bladder Cancer, Despite Guidelines
Guidelines that recommend de-escalating surveillance in patients with low risk non–muscle-invasive bladder cancer are being ignored by clinicians. Medscape Medical News
