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Wednesday, June 29, 2022

Simple Urine Test Could Improve Detection of Bladder Cancer

A test that detects a biomarker in urine samples has shown excellent performance for the detection of bladder cancer in two independent studies. Medscape Medical News

Overuse of Surveillance in Bladder Cancer, Despite Guidelines

Guidelines that recommend de-escalating surveillance in patients with low risk non–muscle-invasive bladder cancer are being ignored by clinicians. Medscape Medical News

Bladder Cancer Need Not Always Require Radical Cystectomy

Researchers involved in a large cohort study from three major institutions are calling for broader use of trimodal therapy for muscle-invasive bladder cancer. Medscape Medical News

COVID Has Led to Big Declines in Cancer Screenings, New Diagnoses

The large study helps quantify the extent to which the pandemic has affected new diagnoses of prostate, lung, bladder, and colorectal cancers in 2020. Medscape Medical News

How to Avoid Cystectomy in Muscle-Invasive Bladder Cancer

Nearly half the patients with muscle-invasive bladder cancer had clinical complete responses, showing that bladder-intact recurrence-free survival is possible. Medscape Medical News

To Stay: Two More Cancer Indications With ‘Dangling Approvals’

On the second day of a historic meeting, FDA advisers voted to keep the accelerated approvals for two immunotherapies for use in bladder cancer. Medscape Medical News

Bladder Cancer Indication Withdrawn for Durvalumab

AstraZeneca is withdrawing durvalumab's indication for the treatment of metastatic bladder cancer after a phase 3 trial showed no survival benefit. Medscape Medical News

If PPIs Are Onboard, Atezolizumab May Not Work for Bladder Cancer

Your patients with atezolizumab-treated bladder cancer may not benefit if they are on a PPI. Medscape Medical News

DNA-Methylation Test Shows Promise in Bladder Cancer Detection, Monitoring

An assay using methylation markers may offer an alternative to more costly, invasive methods for bladder cancer detection and surveillance, according to a new study. Reuters Health Information

Gene Therapy Shows Good Results in BCG-Unresponsive NMIBC

An investigative intravesical viral gene therapy could be a bladder-sparing alternative for some patients with high-grade, nonmuscle invasive bladder cancer (NMIBC), results from a phase 3 study show. Medscape Medical News

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